Construction of fused bis(pyran) units from enones via a hydrosilylation-dihydroxylation-acetalization-reduction sequence.
نویسندگان
چکیده
HWE coupling of two simple bifunctional fragments provides enones that can be subjected to a four-step sequence to furnish trans-fused bis(pyrans) in good overall yield.
منابع مشابه
Directed and undirected asymmetric dihydroxylation reactions: application in the synthesis of a C-linked analogue of allolactose.
The complex OsO4.(S,S)-1,2-diphenyl-N,N'-bis(2,4,6-trimethylbenzyl)ethane-1,2-diamine is an effective reagent for the desymmetrisation of meso-1,2-bis(3,6-dihydro-2H-pyran-2-yl)ethanes by asymmetric dihydroxylation; this process, whose sense of diastereoselectivity depends on substitution and stereochemistry, has been exploited in the synthesis of a C-linked analogue of allolactose.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 شماره
صفحات -
تاریخ انتشار 2006